Reference range: Which statistical intervals to use?
نویسندگان
چکیده
منابع مشابه
Prerequisites for use of common reference intervals.
The theory of reference values was developed more than 30 years ago, but its application in most clinical laboratories is still incomplete today. This is for several reasons, the most relevant ones being the lack of standardisation of the analytical methods, resulting in method-dependent values, and the difficulty in recruiting the proper number of reference subjects for establishment of refere...
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This paper explains how to select the correct statistical test for a research project, clinical trial, or other investigation. The first step is to decide in what scale of measurement your data are as this will affect your decision-nominal, ordinal, or interval. The next stage is to consider the purpose of the analysis-for example, are you comparing independent or paired groups? Several statist...
متن کاملWhich statistical tests should I use?
Statistical tests can be powerful tools for researchers. They provide valuable evidence from which we make decisions about the significance or robustness of research findings. Statistical tests are a critical part of the answers to our research questions and ultimately determine how confident we can be in the evidence to inform clinical practice. In addition to analysing data to answer research...
متن کاملPartitioning reference intervals by use of genetic information.
BACKGROUND Reference intervals that incorporate genetic information could reduce the misidentification of unusual test results caused by non-disease-associated genetic variation and increase the detection of results indicating underlying pathology. Subdividing reference groups by genetic effects, however, may lead to increased uncertainty around reference interval endpoints (because of the smal...
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RATIONALE, AIMS AND OBJECTIVES Reference intervals provided by the laboratory are commonly established by measuring samples from apparently healthy subjects in the ages 18-65 years, excluding elderly individuals with chronic diseases and medication. The aim of our study was to establish whether current reference intervals for immune parameters and chemical biomarkers are valid for older individ...
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ژورنال
عنوان ژورنال: Statistical Methods in Medical Research
سال: 2020
ISSN: 0962-2802,1477-0334
DOI: 10.1177/0962280220961793